Abstract #0381

Tony Stoecker^{1},
Kaveh Vahedipour^{1}, Eberhard Pracht^{1}, Daniel Brenner^{1},
N. Jon Shah^{1,2}

^{1}Institute of
Neuroscience & Medicine - 4, Forschungszentrum Juelich, Juelich, Germany;
^{2}Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen
University, Aachen, Germany

Mapping of relaxation times and proton density with
high isotropic resolution is best performed with a 3D acquisition and, thus,
short TR. As refocusing of transverse magnetization is unavoidable in such
approaches, accurate quantification needs a signal equation accounting for T_{2}.
Here, the DESS sequence was chosen, where every Nth pulse was replaced by a
180 magnetization preparation pulse (MP-DESS). The echoes between two
MP-pulses are segmented into several images along the recovery. A proper
signal equation is given by the extended phase graph. The resulting
least-squares fit yields accurate T_{1}, T_{2}, and M_{0}
maps in vivo.