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Abstract #0525

Real Time Respiration Based Steering for High Intensity Focused Ultrasound in the Liver

Andrew B. Holbrook1,2, Charles L. Dumoulin3, Juan M. Santos4, Yoav Medan5, Kim Butts Pauly1

1Radiology, Stanford University, Stanford, CA, USA; 2Bioengineering, Stanford University, Stanford, CA, USA; 3University Cincinnati College of Medicine, Imaging Research Center, Cincinnati, OH, USA; 4HeartVista, Palo Alto, CA, USA; 5InSightec, Tirat Carmel, Israel


High Intensity Focused Ultrasound (HIFU) treatment of the liver during free breathing requires maintenance of the ultrasound focus on the desired target. We propose a model-based method utilizing a respiratory belt to provide the respiratory position, which is used to find the target and transducer positions from a lookup table acquired before treatment. The method was tested in a gel phantom moving back and forth over a fixed external transducer and compared to ablations without steering and ablations without motion. The steered ablation produced a much tighter focus compared to the one not steered.

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