Meeting Banner
Abstract #0585

Susceptibility Mapping of the Substantia Nigra in Parkinson Patients At 7T After One Year of Diagnosis & Treatment

Andreas Schfer1, Derek V. Ott2, Almut Focke2, Johannes Schwarz2, David Weise2, Robert Turner1, Sonja A. Kotz1

1Max-Planck-Institute for Human Cognitive & Brain Sciences, Leipzig, Germany; 2University Hospital, Leipzig, Germany

Pathological studies have shown that the iron content in the Substantia Nigra is increased in Parkinson patients. It has been shown that susceptibility mapping may indicate a higher iron concentration of the SN in vivo in clinically diagnosed but not medicated PD patients compared to young healthy volunteers. Here we present results of a continuing study by calculating the susceptibility of the SN of an age-matched control group, and also comparing the susceptibility values of the patients after one year of diagnosis and treatment.