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Abstract #0734

Liver Fat & Water MR T2 Values at 3T: Dependence Upon Steatosis Level

Andrew James Gilman1, Aliya Qayyum1, Michelle Nystrom1, Susan Moyher Noworolski1

1Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA

While T2 decay times are known to change between tissues and with disease, liver T2fat and T2water and their dependence on steatosis havent been reported at 3T. T2 values were calculated from multiple-echo 3T MR liver spectra in 12 NAFLD patients and 3 healthy controls. T2fat (62.99.8ms) was much higher than T2water(27.24.0ms). With increasing MRS fat fraction, T2fat tended to increase (p<0.075) while T2water significantly decreased (p<0.04). Similar correlations were observed versus the patients histologically determined steatosis grades. This suggests the importance of accounting for T2 when acquiring liver MRS because of its dependency upon measurement technique and disease state.