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Abstract #0788

Spin- & Gradient-Echo EPI for Imaging of Brain Perfusion with MRI

Heiko Schmiedeskamp1, Matus Straka1, Greg Zaharchuk1, Nancy J. Fischbein1, Marteen G. Lansberg2, Jean-Marc Olivot2, Greg W. Albers2, Michael E. Moseley1, Roland Bammer1

1Department of Radiology, Stanford University, Stanford, CA, USA; 2Department of Neurology, Stanford University, Stanford, CA, USA

A spin- and gradient-echo (SAGE) EPI sequence was used for simultaneous acquisition of spin- and gradient-echo weighted perfusion maps through the acquisition of 5 echo trains per readout. Hereby, perfusion parameters were calculated from estimates of R2 and R2*, rather than relative changes in signal intensity, with the goal to produce T1-independent, more quantitative PWI maps and to facilitate vessel size imaging.