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Abstract #0824

In Vivo T1ρ Study on Human Kidney

Xiang He1, Chan-Hong Moon1, Jung-Hwan Kim1, Kyongtae Ty Bae1

1Department of Radiology, University of Pittsburgh, Pittsburgh, PA, United States

In this study, we improved the T1ρ sequence to compensate for both B0 and B1 field imperfections and applied this technique in the first time for T1ρ-weighted imaging and T1ρ mapping of in vivo human kidneys. Our result demonstrated that T1ρ signal of the kidney may provide additional information regarding the underlying structure of the kidney beyond the traditional T1, T2 and T2* measurement, and may serve as an important imaging biomarker for quantitative functional MRI of kidney. Additionally, the sensitivity of T1ρ to tissue compositions and interactions may broaden our understanding and detection of renal pathologies.