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Abstract #0851

Rapid, Volumetric Segmentation of Visceral Adipose Tissue with Quantitative Chemical Shift MRI at 3T

Aziz H. Poonawalla1, Brett P. Sjoberg1, Michael Schroeder1, Diego Hernando1, Pablo Irarrazaval1,2, Scott Brian Reeder1

1Radiology, University of Wisconsin, Madison, WI, United States; 2Biomedical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile

Quantitative measurement of visceral adipose tissue (VAT) is demonstrated using a volumetric chemical-shift fat/water imaging method with corrections for relaxation effects and accurate spectral modeling of fat. Fat, water and quantitative fat-fraction images were acquired over the entire abdomen and pelvis at 3T with a 32-channel phased array in a single 26-sec breath-hold. Robust VAT volumes were measured semi-automatically with <30 min post-processing, with strong correlation (r2 = 0.99) to manually-segmented VAT requiring ~4 hours.