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Abstract #0884

Improved Separation & Quantification of Xe-129 Dissolved-Phase Resonances in the Lung

Jaime Mata1, Kai Ruppert1, Peter Sylvester1, Isabel Dregely2, Talissa Altes1, Iulian Ruset2, William Hersman2, Grady Miller1, Steve Ketel2, Jeff Ketel2, John Mugler III1

1Radiology, University of Virginia, Charlottesville, VA, United States; 2Xemed, LLC, Durham, NH, United States

Using hyperpolarized Xe-129 gas and Chemical Shift Imaging, we directly calculate images reflecting the amount of Xe-129 in the airspaces, and dissolved in the lung tissue, Red Blood Cells (RBC), and other compartments, thus obtaining detailed spatial information regarding how Xe-129 is distributed in those different compartments and providing regional information about lung physiology.