Abstract #0899

Quantitative Imaging of Alveolar Recruitment with Hyperpolarized Gas MRI

Maurizio F. Cereda¹, Kiarash Emami², Stephen J. Kadlecek², Yi Xin², Puttisarn Mongkolwisetwara², Harilla Profka², Amy Barulic², Stephen Pickup², Nicholas N. Kuzma², Masaru Ishii³, Hooman Hamedani², Benjamin M. Pullinger², Rajat Ghosh², Jennia Rajaei², Clifford S. Deutschman¹, Rahim R. Rizi²

¹Anesthesiology & Critical Care, University of Pennsylvania, Philadelphia, PA, United States; ²Radiology, University of Pennsylvania, Philadelphia, PA, United States; ³OtolaryngologyHead & Neck Surgery, Johns Hopkins University, Baltimore, MD, United States

Atelectasis, often caused by a mechanical ventilator, promotes lung injury, whose mechanisms are not fully understood. Understanding these underlying mechanisms requires simultaneous measurements of ventilated air space and alveolar size, which can be achieved through the use of hyperpolarized gas MRI technology. Additionally, this technique can show how alveolar recruitment maneuvers reestablish a normal pattern of airspace inflation.