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Abstract #0920

Manganese: A New Contrast Agent for Lung Imaging?

Oliviero Gobbo1, Magdalena Zurek2, Frederic Tewes1, Carsten Ehrhardt1, Yannick Crmillieux2

1School of Pharmacy & Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, Ireland; 2University of Lyon, CREATIS-LRMN, Lyon, France

A new approach for T1-enhancemened rat lung MR imaging, was evaluated. This technique uses a manganese-based contrast agent combined with a very short echo-time radial MRI. Different concentrations of a contrast agent were investigated. A significant signal intensity enhancement was observed in the MnCl2-instilled lung versus control animals. The manganese can be use as an efficient contrast agent for lung MRI.