Real-Time Multi-Slice MRI of Renal Filtration in the Mouse

Amir Moussavi¹, Martin Uecker¹, Tilman Johannes Sumpf¹, Roland Tammer^1,2, Jens Frahm¹, Susann Boretius¹

To avoid the necessity of respiratory gating, abdominal MRI of the mouse requires short acquisition times. The combination of highly undersampled radial FLASH with a nonlinear inverse image reconstruction algorithm allowed for movies with a temporal resolution of 70 ms per image. Accordingly, dynamic contrast-enhanced studies of the mouse kidney could be performed at high spatial and temporal resolution. Moreover, the approach facilitated the simultaneous coverage of both kidneys by multiple sections.