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Abstract #0950

Real-Time Multi-Slice MRI of Renal Filtration in the Mouse

Amir Moussavi1, Martin Uecker1, Tilman Johannes Sumpf1, Roland Tammer1,2, Jens Frahm1, Susann Boretius1

1Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; 2DFG Research Center for Molecular Biology of the Brain (CMPB), Goettingen, Germany

To avoid the necessity of respiratory gating, abdominal MRI of the mouse requires short acquisition times. The combination of highly undersampled radial FLASH with a nonlinear inverse image reconstruction algorithm allowed for movies with a temporal resolution of 70 ms per image. Accordingly, dynamic contrast-enhanced studies of the mouse kidney could be performed at high spatial and temporal resolution. Moreover, the approach facilitated the simultaneous coverage of both kidneys by multiple sections.