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Abstract #1034

Validation of Susceptibility-Based Models with Field Map Measurements in the Breast

Caroline D. Jordan1,2, Bruce L. Daniel1, Kevin M. Koch3, Huanzhou Yu4, Steve Conolly5, Brian A. Hargreaves1

1Radiology, Stanford University, Stanford, CA, United States; 2Bioengineering, Stanford University, Stanford, CA, United States; 3Applied Science Laboratory, GE, Waukesha, WI, United States; 4Global Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 5Bioengineering, UC Berkeley, Berkeley, CA, United States

MRI is an important tool for the detection, diagnosis and staging of breast cancer. The shape of the breast may result in subject-specific susceptibility-induced field changes due to the air-tissue boundary. We investigated a model-based B0 field map based on magnetic susceptibility to determine subject-specific field inhomogeneities in the breast. Quantitative results of 10 healthy female volunteers at 3T indicate that the computed field map closely models the inhomogeneities of the measured field map. This rapid computation may provide a field map estimate for improved breast shimming or for choosing scanning input parameters.