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Abstract #1051

High Resolution Ex Vivo MRI of Prostate Specimen, Correlation with Whole-Mount Histology & In Vivo MRI

Chad R. Haney1, Xiaobing Fan1, Garima Agrawal1, Charles A. Pelizzari2, Gregory S. Karczmar1, Jonathan Bakst3, Tatjana Antic3, Scott E. Eggener4, Aytekin Oto1

1Radiology, University of Chicago, Chicago, IL, United States; 2Radiation & Cellular Oncology, University of Chicago, Chicago, IL, United States; 3Pathology, University of Chicago, Chicago, IL, United States; 4Urology/Surgery, University of Chicago, Chicago, IL, United States


Histology is the gold standard for assessing the presence or absence of cancer in prostatectomy specimen. However, the entire prostate cannot be processed and the histological processing often damages the specimen. High-resolution ex vivo MRI of the prostate can not only serve as a bridge to registering in vivo MRI with histology but can provide additional diagnostic information. We present preliminary results from 8 patients that suggests date suggest that high resolution T2-weighted ex vivo MRI differentiates between carcinoma and benign prostatic hyperplasia.