Evaluations of Human Prostate Cancer Metabolomic Profiles with a Testing Cohort.

Elita DeFeo¹, Johannes Kurth¹, Chin-Lee Wu, Shulin Wu, W. Scott McDougal², Leo L. Cheng³

Our 2005 publication on the investigations of human prostate cancer meabolomics led to two major conclusions that metabolomic profiles can differentiate tissue specimens with and without cancer glands, as well as patient pathological stages. However, this study only proposed the metabolomic structure from the analysis of a training cohort and did not evaluate another independent testing cohort. In this study we report our analysis of a testing cohort that was measured precisely following the exact experimental procedures that guided the 2005 study for the training cohort.