Mayumi Takeuchi1, Kenji Matsuzaki1, Masafumi Harada1
1Department of Radiology,
We evaluated MR imaging of 30 small early stage cervical cancers at 3T by using diffusion-weighted imaging (DWI) and 3D-dynamic contrast-enhanced MRI. All 21 small visible cancers (1B1, 2A1) and 1 of 9 microscopic diseases (CIS-1A) showed early nodular or thickened mucosa-like enhancement exhibiting hypervascular cancerous foci, whereas 7 of 9 microscopic diseases showed early linear enhancement along the mucosa reflecting atypical vascular proliferation due to angiogenesis of cancer cells. All 21 small visible cancers and 6 of 9 microscopic diseases showed high intensity on DWI reflecting hypercellularity due to cancer cell proliferation.