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Abstract #1119

MRI-Based Assessment of Vertebral Deformity

Eual A. Phillips1, Chamith S. Rajapakse1, Michael J. Wald1, Yusuf A. Bhagat1, Mary B. Leonard2, Felix W. Wehrli1, Mary B. Leonard2

1Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2Childrens Hospital of Philadelphia, Philadelphia, PA, United States

Vertebral fractures are among the most common outcomes of osteoporosis and their presence often indicates an elevated risk for future osteoporotic fractures. The purpose of this study was to evaluate the performance of a custom-built software tool for quantitative morphometry of spine on the basis of mid-line sagittal MR images. Towards this goal, we evaluated the intra-reader reproducibility of computing spinal deformity indices and their associations with age and gender as part of an ongoing translational study.