Abstract #1162

Modeling the Hyperemic Response in Skeletal Muscle fMRI

Kiril Schewzow^1,2, Martin Andreas^2,3, Ewald Moser^1,4, Michael Wolzt², Albrecht Ingo Schmid^1,4

¹MR Center of Excellence, Medical University of Vienna, Wien, Austria; ²Dpt. of Clinical Pharmacology, Medical University of Vienna, Wien, Austria; ³Dpt. of Surgery, Medical University of Vienna, Wien, Austria; ⁴Centre of Medical Physics & Biomedical Engineering, Medical University of Vienna, Wien, Austria

Ischemia and reperfusion in skeletal muscle were studied by BOLD-MRI. In this work, we fitted the EPI time courses of the hyperemic response to ischemia, using similar a function as in DCE-MRI. Several parameters which describe hyperemia were determined from the fit results. Significant differences between muscle groups and the impact of post-occlusive stenosis could be shown.