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Abstract #1182

Calculation of Mechanical Properties of the Inter-Luminal Septum in DeBakey Type III Aortic Dissection from the Behavior of P-Waves Detected by Cine MRI : Application of Seismic Technology onto Medical Image Data

Pietro Valsecchi1, Christof Karmonik2,3, Jean Bismuth2, Mark G. Davies2, Dipan J. Shah2, Bill E. Kline1, Alan B. Lumsden2

1ExxonMobil Upstream Research Company, Houston, TX, United States; 2The Methodist DeBakey Heart & Vascular Center, Houston, TX, United States; 3The Methodist Hospital Neurological Institute, Houston, TX, United States

High post-treatment mortality rates in DeBakey type III aortic dissections (AD) (20% in 3 years after hospital discharge) necessitates a better understanding of biomechanical properties of true (TL) and false lumen (FL) wall for the development of effective treatment. In an effort to create synergy between know-how in the energy industry and the medical community, we took advantage of established seismology techniques to estimate stiffness of the AD intra-luminal septum (IS) using the wall pressure wave. From this, Young's modulus of the IS was found to be approximately a factor 50 lower compared to literature values for healthy aortic wall.