Jelena Bock1, Ramona Lorenz2, Andreas Harloff3, Michael Markl2
1Radiology, Medical Physics, University Medical Center , Freiburg, Germany; 2Radiology, Medical Physics, University Medical Center, Freiburg, Germany; 3Neurology, University Medical Center, Freiburg, Germany
In this study we present initial results regarding the detection of pressure wave changes associated with atherosclerosis by applying 4D aortic pressure difference mapping. This approach was tested in patients with aortic high risk plaques versus healthy young volunteers. Patients data demonstrated similar peak pressure differences but showed altered waveform dynamics which reflect the expected increased aortic stiffness and resulted in earlier diastolic inversion of pressure waves.