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Abstract #1202

Loss of Hemodynamic Information in Intracranial Aneurysms: Phase Contrast MRI in a Real-Size Phantom at Different Spatial Resolutions

Pim van Ooij1,2, Annetje Gudon1,2, Joppe Schneiders1, Marcel C. M. Rutten3, Henk Marquering1,2, Charles B. Majoie1, Ed vanBavel2, Aart J. Nederveen1

1Radiology, Academic Medical Center, Amsterdam, Netherlands; 2Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands; 3Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

In this study 3D phase contrast MRI measurements at different spatial resolutions in a real-size intracranial aneurysm phantom are performed to study the loss of flow information when performing PC-MRI at low resolutions. It is observed that flow properties such as vortices can be measured at low resolutions. Voxel-by-voxel differences between high and interpolated low resolutions, however, increase when decreasing resolution. Furthermore, when velocity derivatives at the phantom wall, needed for wall shear stress estimations, are calculated, small as well as large differences are found. This can result in unreliable wall shear stress estimations.