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Abstract #1208

Imaging CSF Flow using Spin Echo Phase Contrast Velocity Encoded MRI at 3T

Bruce Shawn Spottiswoode1,2, Michael Markl3

1MRC/UCT Medical Imaging Research Unit, Department of Human Biology, University of Cape Town, Cape Town, Western Cape, South Africa; 2Radiology, University of Stellenbosch, Cape Town, Western Cape, South Africa; 3Department of Radiology, Medical Physics, University Medical Center, Freiburg University, Freiburg, Germany

Flow sensitive MRI techniques are typically based on gradient echo (GE) imaging. GE offers a relatively low SNR for imaging cerebrospinal fluid (CSF) because of its long T1 relaxation time. We have developed a spin echo (SE) phase contrast (PC) velocity encoding sequence, and compared this to a standard GE-PC sequence using both phantom and in vivo experiments. SE-PC is only suitable for measuring slow flow because of the relatively long TEs and the need for refocusing pulse crusher gradients. A 2-3 fold increase in SNR has been demonstrated for CSF when comparing the technique to conventional multi-phase GE-PC imaging. Reduced distortions at air-tissue interfaces and improved velocity background contrast in the flow images can also be appreciated.