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Abstract #1221

MR Flow Imaging Beyond the Mean Velocity: Estimation of the Skew & Kurtosis of Intravoxel Velocity Distributions

Petter Dyverfeldt1,2, Andreas Sigfridsson1, Hans Knutsson1, Tino Ebbers1

1CMIV & Linkping University, Linkping, Sweden; 2University of California San Francisco, San Francisco, CA, United States

MR flow imaging has proved to be a valuable tool in improving the understanding and diagnostics of cardiovascular disease. The most common MR flow imaging method is phase-contrast velocity mapping, which estimates the mean velocity of a voxel. However, MR may permit more advances flow analysis. This study goes beyond the mean velocity of a voxel and evaluates the potential of MRI for the quantification of skew and kurtosis of intravoxel velocity distributions. Proof-of-concept is demonstrated based on simulated MR measurements of skew and kurtosis in post-stenotic flow.