Harsh Kumar Agarwal1, Peter Koken2, Michael Schr3, Jing Yu1, Allison G. Hays1, Holger Eggers2, Robert G. Weiss1, Peter Brnert2, Matthias Stuber4,5
1Johns Hopkins University, Baltimore, MD, United States; 2Philips Research Laboratories, Hamburg, Germany; 3Philips Healthcare, Cleveland, OH, United States; 4Department of Radiology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; 5Center for Biomedical Imaging (CIBM), Lausanne, Switzerland
Three Tesla cross-sectional spiral coronary MRI has successfully been used for the measurement of endothelial function in healthy adults and in patients with coronary artery disease. However, increased B0 inhomogeneity at high magnetic field strength may adversely affect the image quality and the quantitative measurements. Therefore, we have combined the 3 point Dixon technique with cross sectional spiral coronary MRI to separate water and fat signal on the one hand and to correct for off-resonance artifacts using sliding window conjugate phase reconstruction on the other hand.