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Abstract #1294

MRI Pulmonary Perfusion Imaging as a Quantitative Predictor of Regional Pulmonary Vascular Resistance in Pulmonary Hypertension

Adam Telfer1, Robin Condliffe2, David Capener1, Andrew Swift1, Smitha Rajaram1, Helen Marshall1, Judith Hurdman2, Charles Elliot2, David Kiely2, Jim Wild1

1Academic Radiology Unit, University of Sheffield, Sheffield, South Yorkshire, United Kingdom; 2Pulmonary Vascular Diseases Unit, Sheffield Teaching Hospitals, Sheffield, South Yorkshire, United Kingdom

This abstract describes a potential method for the non invasive estimation of Pulmonary Vascular Resistance in Pulmonary Hypertension by the use of gadolinium contrast enhanced MRI of the pulmonary vasculature. The key variable is the Time to Peak Signal Intensity (TTP) in the lung fields from initial detection of contrast in the Superior Vena Cava, Right Atrium, Right Ventricle and Pulmonary Artery. The method presented uses perfusion data from a standard contrast enhanced imaging sequence and involves only relatively quick additional calculations which may give it an advantage as a potential clinical tool.