Avinash Kali1, Andreas Kumar2, Xiangzhi Zhou3, Veronica L. M. Rundell3, Ying Liu3, Rachel A. Klein3, Richard L. Q. Tang3, Rohan Dharmakumar3
1Biomedical Engineering, Northwestern University, Chicago, IL, United States; 2Department of Medicine, Laval University, Quebec, QC, United States; 3Radiology, Northwestern University, Chicago, IL, United States
T2 and T2* changes associated with myocardial hemorrhage in the setting of ischemia-reperfusion injury were examined and the effectiveness of the two mapping techniques in discriminating hemorrhage was evaluated using a canine model. T2* of hemorrhagic infarctions were significantly lower than those of non-hemorrhagic infarctions and remote myocardium. T2s of both hemorrhagic and non-hemorrhagic infarctions were significantly elevated with respect to remote myocardium, likely due to the high sensitivity of T2 to myocardial edema. We conclude that T2* maps are more effective at discriminating hemorrhage, while T2 maps are more effective at detecting myocardial edema post ischemia-reperfusion injury.