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Abstract #1316

Estimate of Global Radial, Circumferential & Longitudinal Strain from SSFP Cines: A Study in Controls & Patients with Low to Normal Ejection Fraction

June Cheng-Baron1, Michael D. Nelson2, Corey R. Tomczak3, Kelvin Chow1, Justin A. Ezekowitz4, Mark J. Haykowsky3, D. Ian Paterson4, Richard B. Thompson1

1Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; 2Faculty of Physical Education & Recreation, University of Alberta, Edmonton, Alberta, Canada; 3Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada; 4Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada

We propose surrogates for global longitudinal, circumferential, and radial strains that can be measured from SSFP images based on the change in endocardial and epicardial borders over the entire left ventricle, with minimal additional post-processing. These metrics are compared in controls and patients with a wide range of ejection fractions and with literature values for each strain component. In controls, these metrics agree with literature values. In the patients with preserved ejection fractions, longitudinal function was lower than controls despite no measured difference in EF, circumferential, or radial function. The fractional longitudinal contribution to EF declines with impaired EF.