High-Resolution 1H-FID-MRSI of the Human Brain at 7T

Wolfgang Bogner¹, Stephan Gruber¹, Siegfried Trattnig¹, Marek Chmelik¹

This work describes a new approach for high spatial resolution 1H-MRSI of the human brain at 7T in vivo. The presented method is based on free induction decay (FID) acquisition with an ultra-short echo time (TE) of 1.3ms. This allowed the acquisition of a 6464 matrix in 30 min measurement time. High quality metabolic maps with 3.43.412 mm resolution were obtained not only for NAA, Cho, and Cr, but even for Glu, and mI, due to the ultra-short TE. Our approach is insensitive to T2 decay, J-modulation, B1 inhomogeneities, CSDEs, and overcomes SAR restrictions at ultra-high magnetic fields. This makes it a promising method for high resolution 1H-MRSI at 7T and above.