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Abstract #1459

Mycolates & Phenolic Glycolipids as Biomarker for Tubercular Ascites : A Proton Magnetic Resonance Spectroscopic Approach

Abhinav Arun Sonkar1, Shatakshi Shrivastav2, Raghuvendra Kumar3, Amita Jain4, Raja Roy5

1Surgery, CSM Medical University, Lucknow, Uttar pPradesh, India; 2Center for Bio Magnaetic Resonance , SGPGI, Lucknow, Uttar Pradesh, India; 3Surgery, CSM Medical University( King Georges Medical University), Lucknow, Uttar Pradesh, India; 4Microbiology, CSM Medical University, Lucknow, Uttar Pradesh, India; 5Center for Bio Magnetic Resonance, SGPGI, Lucknow, Uttar Pradeshi, India

Abdominal TB involves the gastrointestinal tract, peritoneum, lymph node or solid viscera, constituting up to 12% of extra pulmonary TB and 1-3% of the total cases of tuberculosis. The disease involves different site/s within the abdomen with different morphologies, making the signs and symptoms of disease, very non-specific. This results in poor prognosis and diagnosis and opens an avenue for investigative research. In the present study, the ascitic fluid obtained from different groups of patients suffering with TB or other benign diseases were studied by 1H NMR spectroscopy to identify the fingerprint biomarker in tubercular ascitis for its differential diagnosis.