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Abstract #1463

Ultra-High Resolution 3D Anatomical MRI of the Ex Vivo Retina at 10x10x14m

Bryan H. De La Garza1, Timothy Q. Duong1

1Research Imaging Institute, Opthamology/Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States

This study explored the use of ultra high-resolution 3D anatomical MRI (MR microscopy) to resolve different layers ex vivo rat retina at a nominal resolution of 10x10x14m. MR microscopy showed multiple distinct bands with remarkable contrast and in excellent agreement with similar histological sections. MRI and histological layer thicknesses were in excellent agreement.