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Abstract #1495

High-Resolution Sodium Imaging of the Human Brain at 4T

Daniel Pascal Fiege1, Christian Carlo Mirkes1, Ana-Maria Oros-Peusquens1, Sandro Romanzetti1, N. Jon Shah1,2

1Institute of Neuroscience & Medicine, Forschungszentrum Jlich, Jlich, NRW, Germany; 2Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, NRW, Germany

Sodium MR images are usually low in resolution due to an inherently low signal-to-noise ratio. We have optimised a Cartesian gradient echo sequence for a nominal 2mm isotropic resolution. Images of a male volunteer acquired in 16 sessions were co-registered and averaged. The resulting sodium images show detailed anatomy and excellent correspondence to proton anatomical reference images.