Abstract #1495

High-Resolution Sodium Imaging of the Human Brain at 4T

Daniel Pascal Fiege¹, Christian Carlo Mirkes¹, Ana-Maria Oros-Peusquens¹, Sandro Romanzetti¹, N. Jon Shah^1,2

¹Institute of Neuroscience & Medicine, Forschungszentrum Jlich, Jlich, NRW, Germany; ²Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, NRW, Germany

Sodium MR images are usually low in resolution due to an inherently low signal-to-noise ratio. We have optimised a Cartesian gradient echo sequence for a nominal 2mm isotropic resolution. Images of a male volunteer acquired in 16 sessions were co-registered and averaged. The resulting sodium images show detailed anatomy and excellent correspondence to proton anatomical reference images.