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Abstract #1527

In Vitro Skin Penetration Measurement with Contrast-Enhanced MRI at 7 Tesla

Maximilian N. Voelker1, Jan M. Burg2, Peggy Schlupp3, Ulf Maeder, Alexander M. Koenig1, Johannes T. Heverhagen1

1Diagnostic Radiology, Philipps University Marburg, Marburg, Hessen, Germany; 2 Institute of Medical Physics & Radiation Protection, University of Applied Sciences Giessen-Friedberg, Giessen, Germany; 3Institute of Biopharmaceutical Technology, University of Applied Sciences Giessen-Friedberg, Giessen, Germany


The penetration of MRI contrast agents into the skin can be measured directly by MRI. With a submicron emulsion as carrier system the efficiency and the dynamics of a Drug Carrier System on the penetration of a topically applied contrast agent can be assessed.

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