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Abstract #1540

Correlation of Post-Stimulus Undershoot with BOLD Response in Event-Related FMRI

Xiaopeng Zong1, Jie Huang1,2

1Department of Radiology, Michigan State University, East Lansing, MI, United States; 2Neuroscience Program, Michigan State University, East Lansing, MI, United States

Event-related (ER) BOLD-fMRI offers a means for quantitatively investigating the relationship between the elicited BOLD response and the corresponding brief neural events. The dynamic ER-BOLD response increases for a few seconds and then decreases to baseline, followed by a negative undershoot before returning to the baseline. Using an ER paradigm with voxelwise analysis, this study found that the dynamic BOLD response was highly homogeneous across V1, V2 and V3 and the negative undershoot was correlated with the positive BOLD response in each visual area, suggesting a common impulse hemodynamic response across the visual areas.