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Abstract #1555

Simultaneous Intracranial EEG-fMRI in Humans: Data Quality

David William Carmichael1, Serge Vulliemoz1,2, Roman Rodionov1, Karin Rosenkranz1, Andrew McEvoy3, Louis Lemieux1,4

1Clinical & Experimental Epilepsy, UCL Institute of Neurology, London, United Kingdom; 2Epilepsy Unit, University Hospital & University of Geneva, Geneva, Switzerland; 3Victor Horsley Dept. Neurosurgery, National Hospital for Neurology & Neurosurgery, London, United Kingdom; 4MRI Unit, National Society for Epilepsy, Chalfont St. Peter, United Kingdom

We aimed to record intracranial EEG and fMRI concurrently to study physiological and pathological activity at a greater range of spatial and temporal scales. However, technical challenges of safety and data quality remain. In this abstract, we report first results in two patients with epilepsy, implanted for presurgical evaluation, with reference to safety and data quality. Intracranial EEG quality was high with standard scalp EEG scanner-artifact correction methods, in particular cardiac-related artifacts were small compared to epileptic events. Although fMRI data quality was reduced close to electrode contacts on average >50% signal was observed 5mm from the electrode contact locations.