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Abstract #1560

Evoked & Induced Somatosensory EEG Responses Predict Activity in Resting State Networks in Simultaneous fMRI Data During Median Nerve Stimulation.

Stephen D. Mayhew1, Karen J. Mullinger2, Andrew P. Bagshaw1, Richard W. Bowtell2, Susan T. Francis2

1Birmingham University Imaging Centre, School of Psychology, University of Birmingham, Birmingham, United Kingdom; 2Sir Peter Mansfield Magnetic Resonance Centre, School of Physics & Astronomy, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom

Here we investigate the interaction of resting state networks with both somatosensory evoked potentials (SEP) and induced mu oscillatory EEG responses during sustained median nerve stimulation recorded using simultaneous EEG-fMRI. The default-mode-network (DFM) and dorsal attention network (DAN) were identified from group ICA of the BOLD data. Strong spatial overlap was observed between: 1) DFM IC and positive BOLD-SEP correlation; 2) DAN IC and negative BOLD-mu rhythm correlations. Fluctuations in BOLD signal in the DFM and DAN were found to correlate with SEPs and mu rhythm, suggesting that these reflect functionally relevant variations in task engagement and attention.