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Abstract #1597

Functional Network of Hand Prehension : Validation by fMRI Network Connectivity

Tzu-Chen Yeh1,2, Chou-Ming Cheng1, Bi-Yu Hsu1, Jo-Mei Huang2

1Department of Medical Research & Education, Taipei Veterans General Hospital, Taipei, Taiwan; 2Insitute of Brain Science, National Yang-Ming University, Taipei, Taiwan

Prehension is defined as the capacity to reach and grasp which involves complex neuro-coginitive architectures. Hand prehension is composed of selection of grasp model and transformation of motor command. Wide network of motor hierarchy involves action initiation of parietal cortices, premotor, supplementary motor area and primary motor cortex. A visuo-motor flanker task was implemented for the fMRI study to validate the prehension control model via dorsal stream. By lag correlation of the prehension-related components derived from spatial independent component analysis, the functional network of hand prehension echoed the theoretical construct and demonstrated major and minor connectivity of functional correlates.