Meeting Banner
Abstract #1740

In-Vivo MR Guided High Intensity Focused Ultrasound Ablation of Pig Liver Tissues: Preliminary Results of a Survival Study.

Frederic Courivaud1, Airazat M. Kazaryan1, Alice Lund2, Per Steinar Halvorsen1, Bjrn Edwin1, Per Kristian Hol1

1The Intervention Centre, Oslo University Hospital, Oslo, Norway; 2Department of Pathology, Oslo University Hospital, Oslo, Norway

Colorectal cancer has a high incidence and is a common cause of cancer death. Surgical removal of colorectal cancer metastases in the liver improves survival rate of these patients but cannot be applied in many cases. MR guided High Intensity Focused Ultrasound (HIFU) is a promising minimal invasive alternative to surgery. However, substantial work is still needed to validate this approach. We demonstrate in this survival study a method to apply HIFU ablation using several sonication cycles during mechanically controlled breath-hold periods on anaesthetized pigs. Ablation is confirmed by MRI and histopathology one week after HIFU treatment.