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Abstract #1744

Quality Assurance of Volumetric Feedback MR-Guided HIFU Ablation Technique in Human Uterine Fibroids

Heikki Juhani Nieminen1, Charles Mougenot2, Bilgin Keserci3, Jouko Soini1, Sham Sokka4, Max Oskar Khler1, Teuvo Vaara1

1Philips Healthcare, Vantaa, Finland; 2Philips Healthcare, Bordeaux, France; 3Philips Healthcare, Seoul, Korea, Republic of; 4Philips Healthcare, Andover, MA, United States

The most common clinical application of Magnetic Resonance guided High Intensity Focused Ultrasound (MR- HIFU) is the thermal ablation of uterine fibroids. The spatial targeting and thermal dose volume accuracies of the volumetric feedback procedure are here studied based on data acquired in a clinical study with 33 patients and a total of 38 symptomatic fibroids. Based on an analysis of the ablated volumes produced by the 471 sonications performed with the Philips Sonalleve MR-HIFU system, the accuracy appears to be better than the imaging resolution,, which is acceptable compared to typical fibroid sizes of 3-15cm in diameter.