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Abstract #1810

MR-Based Attenuation Correction in an Animal for Radiotracer Quantification

Mark Jason Hamamura1, Hon J. Yu1, Seunghoon Ha1, Werner W. Roeck1, James W. Hugg2, Douglas J. Wagenaar2, Dirk Meier3, Bradley E. Patt2, Orhan Nalcioglu1,4

1Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, CA, United States; 2Gamma Medica, Inc. (Clinical Division), Northridge, CA, United States; 3Gamma Medica, Inc. (Industrial Division), Fornebu, Norway; 4Department of Cogno-Mechatronics Engineering, Pusan National University, Pusan, Republic of Korea

Accurate radiotracer quantification in SPECT and scintigraphy requires attenuation correction (AC) of the nuclear projection data. In this study, we acquired MR and scintigraphic images of two vials containing 99mTc sestimibi implanted in a rat using a novel MR-SPECT system. The MRI data was then used to perform AC of the scintigraphic data. The results demonstrate improved accuracy for radiotracer quantification when performing AC using data acquired from simultaneous MR and SPECT imaging.