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Abstract #1891

In Vivo Quantification of Renal Sodium Concentration with a Dual RF Resonator System

Raffi Kalayciyan1, Friedrich Wetterling1, Sabine Neudecker2, Lothar R. Schad1

1Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany; 2Medical Research Center, Heidelberg University, Mannheim, Germany

The quantification of local Tissue Sodium Concentration (TSC) can serve as a diagnostic measure for renal diseases, because TSC is strongly linked to the corticomedullary function regulating the vascular ion concentrations. In this work, for the TSC quantification the required homogeneous B1 is achieved by a dual RF resonator system composed of a newly-developed low noise preamplifier receive-only coil without the need to tune and match, that was used in conjunction with a commercial transmit birdcage volume resonator. The TSC quantification in the rat kidney was illustrated through TSC maps using 3D-UTE sequence.