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Abstract #1952

High Resolution Multiple Slice Composite Inner Volume Excitation Echo Planar Diffusion Weighted Imaging

Hing-Chiu Chang1,2, Tzu-Cheng Chao3, Yi-Jui Liu4,5, Kuo-Fang Shao5, Cheng-Chieh Cheng2, Chao-Chun Lin2,6, Hsiao-Wen Chung2,7

1Global Applied Science Laboratory, GE Healthcare, Taipei, Taiwan; 2Institute of Biomedical Electronics & Bioinformatics, National Taiwan University, Taipei, Taiwan; 3Department of Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States; 4Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan; 5Master's Program in Biomedical Informatics & Biomedical Engineering, Feng Chia University, Taichung, Taiwan; 6Department of Radiology, China Medical University Hospital, Taichung, Taiwan; 7Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan

Reduced field of view (rFOV) technique has been known for its advance in shortening the read-out train in MR imaging. With this excitation scheme, high resolution Echo Planar Imaging (EPI) becomes available with less geometric distortion. In this work, a multiple slice rFOV sequence was proposed with multiple sequential volume acquisition to combine the rFOV images as a full FOV image with appropriate intensity correction to compensate the effect of RF profile imperfection during excitation. And a high resolution in vivo EP-DTI dataset with tractography result was demonstrated to confirm the feasibility of this proposed scheme on clinical research.