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Abstract #1954

A 3D Radial FSE-Based SPLICE Sequence for MR Diffusion Imaging

Jiangsheng Yu1, Yiqun Xue1, Mark A. Rosen1, Hee Kwon Song1

1Department of Radiology, University of Pennsylvania School of Medicine, , Philadelphia, PA, United States

Currently, the gold standard technique for in vivo diffusion imaging is single-shot diffusion-weighted EPI (DW-EPI). However, DW-EPI is sensitive to off-resonance effects, and artifacts are often observed, particularly near air-tissue boundaries. While FSE-based diffusion methods have also been proposed, CPMG conditions can become easily violated, particularly in the presence of motion during diffusion sensitization. The SPLICE technique was recently developed to overcome these artifacts. In this work, we present preliminary results of a hybrid 3D radial FSE SPLICE technique and demonstrate improved ADC maps in both phantom and in vivo experiments.