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Abstract #1958

Distortion Free High Resolution In Vivo Whole Brain Diffusion Tensor Image on 7.0T MRI

Se-Hong Oh1, Jun-Young Chung1, Sung-Yeon Park1, Joshua Haekyun Park1, Dae-Hoon Kang1, Myung-Ho In2, Maxim Zaitsev3, Oliver Speck2, Young-Bo Kim1, Zang-Hee Cho1

1Neuroscience Research Institute, Gachon University of Medicine & Science, Incheon, Korea, Republic of; 2Department of Biomedical Magnetic Resonance, Institute for Experimental Physics, Otto-von-Guericke University Magdeburg, Magdeburg, Germany; 33 Department of Radiologic Research, Medical Physics, University Hospital of Freiburg, Freiburg, Germany

Diffusion pulse sequences based on single-shot EPI inherit virtually all of the artifacts associated with EPI. For example, distortion caused by magnetic susceptibility variations and B0 field inhomogeneity is frequently observed in the frontal sinus. When high resolution at higher magnetic field imaging like 7.0T, diffusion weighted images severely suffer from distortions due to susceptibility artifacts. Therefore, to acquire high resolution DTI images at 7.0T UHF MRI, we should solve geometric distortion problem. To correct geometric distortion use distortion and non-distortion dimensional combined PSF correction method. Then we can correct the geometric distortion both compressed and stretched area more accurately. These results show the efficacy of distortion correction for the anatomical accuracy of fiber tractography. With 7.0T distortion free high-resolution DWI data, we are able to visualize anatomically accurate fiber tractography image as well as small fiber tractography image such as mammillo thalamic tract, which not achievable at low field MRI (i.e. 1.5T or 3.0T).