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Abstract #1989

Stroke Analysis by Means of Kurtosis Diffusion Imaging in In Vivo Animal Studies

Farida Grinberg1, Ezequiel Farrher1, Luisa Ciobanu2, Franoise Geffroy2, N. Jon Shah1,3

1Institute of Neuroscience & Medicine - 4, Forschungszentrum Juelich GmbH, 52425 Juelich, NRW, Germany; 2Neurospin, CEA, Gif sur Yvette, France; 3Department of Neurology, Faculty of Medicine, RWTH Aachen University, JARA, 52074 Aachen, Germany

DKI is a novel method that is considered as the simplest extension of DTI that enables one to quantify deviations from Gaussian diffusion of water molecules in brain tissue. Our results have shown that DKI has a potential to better characterize a pathological state of the brain in animals that have experienced stroke.