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Abstract #2008

Diffusion Imaging In Vivo with Whole-Body Gradient Amplitude of 65 MT/m

Ek Tsoon Tan1, Wesley M. Skeffington1, Juan Sabate1, Bruce D. Collick2, Song Chi1, Rixin Lai1, Christopher J. Hardy1, Luca Marinelli1, Thomas K. Foo1

1GE Global Research, Niskayuna, NY, United States; 2GE Healthcare, Waukesha, WI, United States

A higher performance gradient driver system was developed, capable of delivering gradient amplitude of 65 mT/m in a conventional whole-body MRI system. Imaging at 65 mT/m was compared against the standard 50 mT/m in diffusion MRI. Diffusion images were acquired in two human subjects at b-values of 1000-10000 sec/mm2. As compared to 50 mT/m, imaging with 65 mT/m provided SNR improvements of 7-20% in white matter.