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Abstract #2040

In Vivo Correlation between Non-Model-Based Parameters & Model-Based Ktrans in Brain Tumors

Chih-Feng Chen1, Lin-Wei Hsu2, Ho-Lin Liu2

1Department of Radiology, Chang Gung Memorial Hospital, Chiayi, Taiwan, Taiwan; 2Department of Medical Imaging & Radiological Sciences Institute of Medical Physics & Imaging Sci, Chang Gung University, Taoyuan, Taiwan, Taiwan

The most common estimated parameters in DCE-MRI are Ktrans and Ve. The process of Ktrans estimation is not easy. but the IAUC is more feasible. In this study, we aim to further investigate the application of mIAUCktrans in clinical and find the correlation between mIAUCktrans and Ktrans. With the correlation coefficients of 0.95, mIAUCktrans was more correlated with Ktrans. Since the high correlation between Ktrans and mIAUCktrans was demonstrated in this study, it reveals that mIAUCktrans could be an alternative for physiological condition evaluation in DCE-MRI.