Abstract #2042

Value of Semi-Quantitative Analysis of Dynamic Contrast-Enhanced MRI for Diagnosing Staging of Nasopharyngeal Carcinoma & Comparison with PET-CT

Bingsheng Huang¹, Pek Lan Khong¹, Chung-Sing Wong¹, Dora Lai Wan Kwong², Queenie Chan³

¹The University of Hong Kong, Hong Kong Island, Hong Kong SAR, Hong Kong; ²Clinical Oncology, the University of Hong Kong; ³Philips Healthcare

Dynamic Contrast-enhanced MRI (DCE-MRI) is useful for estimating the tumor malignancy because the contrast enhancement pattern reflects the perfusion and permeability of the tumor as well as the tumor angiogenesis. In this study we investigated the relationship between semi-quantitative contrast enhancement parameters in dynamic DCE-MRI and the diagnosing staging of nasopharyngeal carcinoma, and the correlation between these parameters and PET-CT scanning. Our results showed that some parameters from semi-quantitative analysis of DCE-MRI significantly correlate with the T stages of NPC tumors, but not with PET-CT parameter.