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Abstract #2058

Dynamic Contrast Enhanced MRI of the Brain at 7T

Lars Gerigk1, Hendrik Laue2, Lydia Schuster1, Thomas Hauser1, Ann-Kathrin Homagk3, Armin Nagel3, Marco Essig1, Heinz-Peter Schlemmer1, Michael Bock3

1Radiology, German Cancer Research Center, Heidelberg, Baden-Wrttemberg, Germany; 2Institute for Medical Image Computing, Fraunhofer MEVIS, Bremen, Germany; 3Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Baden-Wrttemberg, Germany

Since vascularization is essential in tumors, analyzing the amount and distribution of tissue perfusion is important to understand tumor growth and to monitor therapies. At lower field strengths, DCE-MRI has been used successfully to quantify permeability and flow, but has been limited in spatial resolution. To make use of the higher signal strength, we adapted this technique to a 7 T whole body system and applied it to patients with brain tumors. Due to the high spatial resolution at 7 T, tumor heterogeneity can be visualized.