Pascal Sati1, Afonso C. Silva2,
Maria I. Gaitan1, Jillian E. Wohler3, Colin Denis Shea1,
Iordanis E. Evangelou1, Luca Massacesi1,4, Peter van
Gelderen5, Jeff H. Duyn5, Steven Jacobson3,
Daniel Salo Reich1
1Translational
Neuroradiology Unit , Neuroimmunology Branch, NINDS, National Institutes of Health,
Bethesda, MD, United States; 2Cerebral Microcirculation Unit,
LFMI, NINDS, National Institutes of Health, Bethesda, MD, United States; 3Viral
Immunology Section, Neuroimmunology Branch, NINDS, National Institutes of
Health, Bethesda, MD, United States; 4Department of Neurology,
University of Florence, Florence, Italy; 5Advanced MRI section,
LFMI, NINDS, National Institutes of Health, Bethesda, MD, United States
The common marmoset (Callithrix jacchus) has a gray-to-white-matter ratio close to that of humans, making it an ideal nonhuman primate for visualizing, in vivo and noninvasively, myelinated structures. Thus, the marmoset has been increasingly studied with MRI. In this work, T2* and phase contrast were explored in marmoset brain. A striking heterogeneous pattern, potentially related to fiber orientation, was observed in posterior WM areas. The marmoset brain is therefore an interesting system in which to study the mechanisms of T2* and phase contrast.
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