Determining the Optimal Label Duration of Pseudo-Continuous ASL at 7 Tesla

Eidrees Ghariq¹, Wouter M. Teeuwisse¹, Andrew Webb¹, Matthias J. P. van Osch¹

High field MRI holds promises for better SNR in ASL applications due to the prolonged blood T1. To fully reach this gain in SNR the label duration must be chosen optimally. In the present study we determined theoretically and experimentally the optimal label duration for pseudo-continuous ASL at 7Tesla. The optimal label duration was found in vivo to be approximately 1500ms, which is lower than the optimal theoretical value around 3000ms. This can probably be attributed to sub-optimal robustness in label efficiency, which in the end results in a shift of the optimal SNR to shorter label durations.