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Abstract #2113

Quantification of Arterial & Microvascular Cerebral Blood Volume using Multiphase TrueFISP Based ASL

Lirong Yan1, Cheng Li2, Emily Kilroy1, Felix Werner Wehrli2, Danny J. J. Wang1

1Department of Neurology, University of California Los Angeles, Los Angeles, CA, United States; 2Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

A new method was introduced to measure arterial and microvascular cerebral blood volume (CBV) by combining multiphase trueFISP readout with arterial spin labeling. Both simulation and experimental results demonstrated well preserved longitudinal magnetization of flowing spins, which can be treated as an intravascular contrast agent for CBV measurement. The measured arterial and microvascular cerebral blood volume (CBV) was around 1.5%.